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NaringinCAS: 10236-47-2

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    1 Kilogram
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    1500  Kilogram
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Synonyms: Nvaringin;Momordica grosvenori Extract;schizandra extract;Naringin 98% (HPLC);PolymethoxyLatecl Flavones (Nobiletin);Naringoside;4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy- R-L-mannopyranosyl)-a-D-glucopyranosyl]- oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-,(2S)-;Naringenin 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside];45-diOH-Flavone-7-rhgluc;Naringenin 7-O-neohesperidoside;7-[[2-O-(6-Deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-5-hydroxy-2(S)-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;7-(2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyloxy)-2,3-dihydro-4',5,7-trihydroxyflavone; Classification: Herbal Extract
EINECS: 233-566-4 Molecular Formula: C27H32O14
Melting Point: 166℃ Boiling Point: 928.1 °C at 760 mmHg
Stability: Stable under normal temperatures and pressures. Water Solubility:
Refractive index: -84 ° (C=2, EtOH) Flash Point: 928.1 °C at 760 mmHg
Purity: 98% Appearance: Light yellow to white
HazardClass: Brand Name: Shaanxi Undersun
Packaging & Delivery
Packaging Detail: 1kg per bag, 25kg per drum
Delivery Detail:
Detailed Description

Basic information:

Naringin is the major flavonoidglycoside in grapefruit and gives grapefruit juice its bitter taste. It is metabolized to the flavanonenaringenin in humans. Both naringenin and hesperetin, which are the aglycones of naringin and hesperidin, occur naturally in citrus fruits.

Indications and Uses

Naringin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of selected drug-metabolizing cytochrome P450enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions in vivo. Ingestion of naringin and related flavonoids can also affect the intestinal absorption of certain drugs, leading to either an increase or decrease in circulating drug levels. To avoid interference with drug absorption and metabolism, the consumption of citrus (esp. grapefruit) and other juices with medications is contraindicated.

Naringin, followed by rutin, was the most potent flavonoid inhibitor of VEGF release, which causes angiogenesis, out of 21 flavonoids. When Naringin is treated with potassium hydroxide or another strong base, and then catalyticallyhydrogenated, it becomes a naringin dihydrochalcone, a compound roughly 300-1800 times sweeter than sugar at threshold concentrations.

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